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Cancer

Chemical structure

Cat.No.

Product Name

CAS no.

Target

  • YN320900 Dexamethasone 50-02-2

    Dexamethasone (DHAP) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects.

  • YN290415 Cyclophosphamide 50-18-0

    Cyclophosphamide is a syntheticalkylatingagent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant.

  • YN321723 Hydrocortisone 50-23-7

    Hydrocortisone is a steroid hormone or glucocorticoid produced by the adrenal gland.

  • YN372798 Estriol 50-27-1

    Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells.

  • YN372741 Estradiol 50-28-2

    Estradiol, or more precisely, 17β-estradiol, is a human sex hormone and steroid, and the primary female sex hormone.

  • YN480324 Benzo[a]pyrene 50-32-8

    Benzo[a]pyrene showslung carcinogenicityin animal models, and it is frequently used in chemoprevention studies.

  • YN430358 Thalidomide 50-35-1

    Thalidomide was introduced as a sedative drug, immunomodulatory agent and also is investigated for treating symptoms of many cancers. Thalidomide inhibits an E3 ubiquitin ligase, which is a CRBN-DDB1-Cul4A complex.

  • YN371768 6-Mercaptopurine 50-44-2

    Mercaptopurine is a widely used antileukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA.

  • YN481995 Estradiol benzoate 50-50-0

    Estradiol benzoate is an estradiol analog which binds to the human, murine and chicken ERα with IC50 of 22-28 nM.

  • YN360932 Reserpine 50-55-5

    Reserpine is an inhibitor of multidrug efflux pumps, used as an antipsychotic and antihypertensive drug.

  • YN330348 Chloroquine phosphate 50-63-5

    Chloroquine phosphate is a 4-aminoquinoline anti-malarial and anti-rheumatoid agent, also acting as an ATM activator.

  • YN340250 Niclosamide 50-65-7

    Niclosamide can inhibit DNA replication and inhibit STAT3 with IC50 of 0.7 μM in a cell-free assay. Niclosamide selectively inhibited the phosphorylation of STAT3 and had no obvious inhibition against t...

  • YN374315 D-Ribose(mixture of isomers) 50-69-1

    D-ribose is a naturally occurring sugar involved in producing energy in the body and is also the structural basis of DNA and RNA.

  • YN330289 Aspirin 50-78-2

    Aspirin is a salicylate, and irreversible COX1 and COX2 inhibitor, used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatory medication.

  • YN250905 Floxuridine 50-91-9

    Floxuridine is an antineoplastic antimetabolite, used in the treatment of colon carcinoma and colorectal cancer that has metastasized to the liver.

  • YN290506 Procaine hydrochloride 51-05-8

    Procaine is an inhibitor of sodium channel, NMDA receptor and nAChR with IC50 of 60 μM, 0.296 mM and 45.5 μM, which is also an inhibitor of 5-HT3 with KD of 1.7 μM.

  • YN251971 Benzimidazole 51-17-2

    Benzimidazole is a heterocyclic aromatic organic compound and acts as an important pharmacophore in medicinal chemistry. Benzimidazole derivatives have been reported to possess various biological activities such as anti-cancer, anti-vir...

  • YN372699 5-Fluorouracil 51-21-8

    Fluorouracil (5-Fluoracil, 5-FU) is a DNA/RNA synthesis inhibitor, which interrupts nucleotide synthetic by inhibiting thymidylate synthase (TS) in tumor cells.

  • YN321626 Histamine 51-45-6

    Histamine, an organic nitrogenous compound, is involved in local immune responses regulating physiological function in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus. It is a potent H1 and H2 receptor ag...

  • YN321354 Histamine phosphate 51-74-1

    Histamine acts directly on the blood vessels to dilate arteries and capillaries mediated by both H 1- and H 2-receptors.

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