AZ12672857
Cat. No. :YN320787
CAS No. :945396-55-4
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order@ubiochem.com| Product Name: | AZ12672857 |
| CAS NO.: | 945396-55-4 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 486.57 |
| Molecular Formula: | C₂₆H₃₀N₈O₂ |
| SMILES: | CN(C1=CC=CC2=C1C=NN2)C3=NC(NC4=CC(N5CCOCC5)=CC(N6CCOCC6)=C4)=NC=C3 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | AZ12672857 is an orally active inhibitor ofEphB4(IC50=1.3nM) and Src kinases. AZ12672857 shows good inhibition of proliferation of c-Src transfected 3T3 cells (IC50=2nM) as well as autophosphorylation of EphB4 in transfected CHO-K1 cells (IC50=9nM). |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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