Gamma-Mangostin
Cat. No. :YN321742
CAS No. :31271-07-5
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Product Name: | Gamma-Mangostin |
CAS NO.: | 31271-07-5 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 396.43 |
Molecular Formula: | C₂₃H₂₄O₆ |
SMILES: | O=C1C2=C(OC3=C1C(C/C=C(C)C)=C(O)C(O)=C3)C=C(O)C(C/C=C(C)C)=C2O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Gamma-Mangostin is a novel competitive5-hydroxytryptamine 2A (5-HT2A) receptorsantagonist, purified from the fruit hull of the medicinal plantGarcinia mangostana. Gamma-Mangostin is a inhibitor ofTransthyretin (TTR) fibrillization, it binds to the thyroxine (T4)-binding sites and stabilized the TTR tetramer. Gamma-Mangostin inhibits [3H] spiperone binding to cultured rat aortic myocytes (IC50=3.5nM) and reduces The perfusion pressure response of rat coronary artery to 5-HT2A (IC50=0.32 µM). |
IC50&Target: | |
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Clinical Trial: | |
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References: |
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