2',5'-Dideoxyadenosine is a potent and non-competitiveadenylyl cyclaseinhibitor via binding the P-site with an IC50 of 3 µM . 2',5'-Dideoxyadenosine is a nucleoside analog and exerts a potentantiadrenergicaction in heart.
SQ22536 is an inhibitor of adenylyl cyclase with an IC50 of 1.4 μM. It can inhibit PGE1-stimulated increases in cAMP levels in intact human platelets.
Fipexide hydrochloride, a parachloro-phenossiacetic acid derivative, is a nootropic drug. Fipexide hydrochloride reduces striataladenylate cyclaseactivity. Fipexide hydrochloride has positive effect on cognitive performance bydopaminergi...
Forskolin is a ubiquitous activator of eukaryotic adenylyl cyclase (AC) in a wide variety of cell types, commonly used to raise levels of cAMP in the study and research of cell physiology.
Small Cardioactive Peptide ...
Small Cardioactive Peptide B (SCPB), a neurally active peptide, stimulatesadenylate cyclaseactivity in particulate fractions of both heart and gill tissues with EC50s of 0.1 and 1.0μM, respectively.
NKH477 (Colforsin dapropate hydrochloride) is a novel water-soluble forskolin derivative that improves cardiac failure mainly through its beneficial effects on diastolic cardiac function. NKH477 directly activates the catalytic unit ...
NKY80 is a potent, selective and non-competitiveadenylyl cyclase (AC)type V isoform inhibitor with IC50s of 8.3 µM, 132 µM and 1.7 mM for type V, III and II, respectively. NKY80 is a non-nucleoside quinazolinone ...
NB001 (HTS 09836) is anadenylcyclase 1 (AC1)inhibitor which has effect on neural and non-neural pain by modulating AC1 activity.
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