YN430041 Ibrutinib 936563-96-1

Ibrutinib (PCI-32765) is a selective, irreversibleBtkinhibitor with an IC50 of 0.5nM.

YN430145 Quizartinib 950769-58-1

Quizartinib (AC220) is an orally active, highly selective and potent second-generation type IIFLT3 tyrosine kinaseinhibitor, with aKdof 1.6nM. Quizartinib inhibits wild-type FLT3 and FLT3-ITD autophosphorylation in M...

YN430101 BI-4464 1227948-02-8

BI-4464 is a highly selective ATP competitive inhibitor of PTK2/FAK , with an IC50 of 17 nM.

YN430193 N-piperidine Ibrutinib hydro... 2231747-18-3

N-piperidine Ibrutinib hydrochloride (Compound 1) is a reversible Ibrutinib derivative. N-piperidine Ibrutinib hydrochloride is a potentBTKinhibitor with IC50s of 51.0 and 30.7nM for WT BTK and C481S BTK, respectiv...

YN430041 Ibrutinib

Ibrutinib (PCI-32765) is a selective, irreversibleBtkinhibitor with an IC50 of 0.5nM.