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Chemical structure


Product Name

CAS no.


  • YN420307 Karanjin 521-88-0

    Karanjin is a major active furanoflavonol constituent ofFordia cauliflora. Karanjin induces GLUT4 translocation in skeletal muscle cells by increasingAMPKactivity. Karanjin can induce cancer cell death through cell cycle arrest ...

  • YN420317 Marein 535-96-6

    Marein has the neuroprotective effect due to a reduction of damage to mitochondria function and activation of theAMPK signal pathway. Marein improves insulin resistance induced by high glucose in HepG2 cells through CaMKK/AM...

  • YN420283 Metformin 657-24-9

    Metformin (1,1-Dimethylbiguanide), a widely used drug for treatment of type 2 diabetes, activates AMP-activated protein kinase (AMPK) in hepatocytes. Metformin promotes mitophagy in mononuclear cells. Metformin indu...

  • YN420286 Buformin 692-13-7

    Buformin (1-Butylbiguanide) is a potent and orally active biguanideantidiabetic agent, anAMPKactivator. Buformin decreases hepatic gluconeogenesis and lowers blood glucose production in vivo. Buformin also has anti-cancer activi...

  • YN420238 Phenformin hydrochloride 834-28-6

    Phenformin HCl is a hydrochloride salt of phenformin that is an anti-diabetic drug from the biguanide class. It activates AMPK, increasing activity and phosphorylation.

  • YN420251 Metformin hydrochloride 1115-70-4

    Metformin HCl decreases hyperglycemia in hepatocytes primarily by suppressing glucose production by the liver (hepatic gluconeogenesis).

  • YN420287 Buformin hydrochloride 1190-53-0

    Buformin hydrochloride (1-Butylbiguanide hydrochloride) is a potent and orally active biguanideantidiabetic agent, anAMPKactivator. Buformin hydrochloride decreases hepatic gluconeogenesis and lowers blood glucose production in v...

  • YN420311 7-Methoxyisoflavone 1621-56-3

    7-Methoxyisoflavone is an isoflavone derivative and also an activator of adenosine monophosphate-activated protein kinase (AMPK).

  • YN420161 AICAR 2627-69-2

    AICAR (Acadesine), an AMPK activator, results in accumulation of ZMP, which mimics the stimulating effect of AMP on AMPK and AMPK kinase. Phase 3.

  • YN420309 Nepodin 3785-24-8

    Nepodin (Musizin) is aquinone oxidoreductase (PfNDH2)inhibitor isolate from Rumex crispus.Nepodin (Musizin) stimulates the translocation of GLUT4 to the plasma membrane by activation of AMPK.Nepodin (Musizin) has antidiab...

  • YN420310 Kahweol 6894-43-5

    Kahweol is one of the consituents of the coffee fromCoffea Arabicawith anti-inflammatory anti-angiogenic, and anti-cancerous activities. Kahweol inhibitsadipogenesis and increase glucose uptake by AMP-activated protein kinase (A...

  • YN420306 Amarogentin 21018-84-8

    Amarogentin (AG), a secoiridoid glycoside mainly extracted from Swertia and Gentiana roots, exhibits anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin is an agonist for the bitter taste receptor T...

  • YN420193 -Gingerol 23513-14-6

    6-Gingerol is the active constituent of fresh ginger known to exhibit a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.

  • YN420303 Euphorbiasteroid 28649-59-4

    Euphorbiasteroid, a component of Euphorbia lathyris L., inhibits adipogenesis of 3T3-L1 cells through activation of the AMPK pathway and induces HL-60 cells to apoptosis via promoting Bcl-2/Bax apoptotic signaling pathway in a ...

  • YN420299 Vaccarin 53452-16-7

    Vaccarin is a major flavonoid glycoside in Vaccariae semen, its biotransformation pathways involves methylation, hydroxylation, glycosylation and deglycosylation.

  • YN420298 Platycodin D 58479-68-8

    Platycodin D is a saponin isolated fromPlatycodi Radix, acts as an activator ofAMPKα, with anti-obesity property.

  • YN420131 COH-SR4 73439-19-7

    COH-SR4 is anAMPKactivator. COH-SR4 shows potent anti-proliferative activities against leukemia, melanoma, breast and lung cancers. COH-SR4 inhibits adipocyte differentiation via AMPK activation, and is promising ...

  • YN420319 SAMS 125911-68-4

    SAMS peptide is a specific substrate for the AMP-activated protein kinase (AMPK).

  • YN420084 Chitosan oligosaccharide 148411-57-8

    Chitosan oligosaccharide (COS) is an oligomer of β-(1→4)-linked D-glucosamine. Chitosan oligosaccharide (COS) activatesAMPK and inhibits inflammatory signaling pathways includingNF-κB and MAPKpathways.

  • YN420315 Cimiracemoside C 256925-92-5

    Cimiracemoside C is an active component ofCimicifuga racemosa, activatesAMPK, has the potential activity against diabetes.


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