Chemical structure
Cat.No.
Product Name
CAS no.
Target
YN420238 Phenformin hydrochloride 834-28-6
Phenformin HCl is a hydrochloride salt of phenformin that is an anti-diabetic drug from the biguanide class. It activates AMPK, increasing activity and phosphorylation.
YN420251 Metformin hydrochloride 1115-70-4
Metformin HCl decreases hyperglycemia in hepatocytes primarily by suppressing glucose production by the liver (hepatic gluconeogenesis).
YN420287 Buformin hydrochloride 1190-53-0
Buformin hydrochloride (1-Butylbiguanide hydrochloride) is a potent and orally active biguanideantidiabetic agent, anAMPKactivator. Buformin hydrochloride decreases hepatic gluconeogenesis and lowers blood glucose production in v...
YN420311 7-Methoxyisoflavone 1621-56-3
7-Methoxyisoflavone is an isoflavone derivative and also an activator of adenosine monophosphate-activated protein kinase (AMPK).
YN420306 Amarogentin 21018-84-8
Amarogentin (AG), a secoiridoid glycoside mainly extracted from Swertia and Gentiana roots, exhibits anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin is an agonist for the bitter taste receptor T...
6-Gingerol is the active constituent of fresh ginger known to exhibit a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.
YN420303 Euphorbiasteroid 28649-59-4
Euphorbiasteroid, a component of Euphorbia lathyris L., inhibits adipogenesis of 3T3-L1 cells through activation of the AMPK pathway and induces HL-60 cells to apoptosis via promoting Bcl-2/Bax apoptotic signaling pathway in a ...
Vaccarin is a major flavonoid glycoside in Vaccariae semen, its biotransformation pathways involves methylation, hydroxylation, glycosylation and deglycosylation.
YN420298 Platycodin D 58479-68-8
Platycodin D is a saponin isolated fromPlatycodi Radix, acts as an activator ofAMPKα, with anti-obesity property.
COH-SR4 is anAMPKactivator. COH-SR4 shows potent anti-proliferative activities against leukemia, melanoma, breast and lung cancers. COH-SR4 inhibits adipocyte differentiation via AMPK activation, and is promising ...
SAMS peptide is a specific substrate for the AMP-activated protein kinase (AMPK).
YN420084 Chitosan oligosaccharide 148411-57-8
Chitosan oligosaccharide (COS) is an oligomer of β-(1→4)-linked D-glucosamine. Chitosan oligosaccharide (COS) activatesAMPK and inhibits inflammatory signaling pathways includingNF-κB and MAPKpathways.
YN420315 Cimiracemoside C 256925-92-5
Cimiracemoside C is an active component ofCimicifuga racemosa, activatesAMPK, has the potential activity against diabetes.
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