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PKC

Chemical structure

Cat.No.

Product Name

CAS no.

Target

  • YN310314 Rottlerin 82-08-6

    Rottlerin, a natural compound purified from Mallotus Philippinensis, is a specific Protein kinase inhibitor with IC50 of 3 μM, 6 μM and 5.3 μM for PKCδ(from baculovirus-infected Sf9 insect cells), PKCδ(from porci...

  • YN310036 D-erythro-Sphingosine 123-78-4

    Sphingosine is an 18-carbon amino alcohol with an unsaturated hydrocarbon chain, which forms a primary part of sphingolipids, a class of cell membrane lipids that include sphingomyelin, an important phospholipid.

  • YN310343 Daphnetin 486-35-1

    Daphnetin, a natural coumarin derivative, is a protein kinase inhibitor, inhibits EGFR, PKA and PKC with IC50 of 7.67 μM, 9.33 μM and 25.01 μM, respectively, also known to exhibit anti-inflammatory and anti-oxidant activi...

  • YN310019 Hispidin 555-55-5

    Hispidin, a PKC inhibitor and a phenolic compound from Phellinus linteus, has been shown to possess strong anti-oxidant, anti-cancer, anti-diabetic, and anti-dementia properties.

  • YN310346 Daphnoretin 2034-69-7

    Daphnoretin (Dephnoretin, Thymelol), a biologically active compound isolated from Wikstroemia indica C.A. Mey., is a protein kinase C (PKC) activator. Daphnoretin inhibits the proliferation, invasion, and migration of tumor cell...

  • YN310169 ζ-Stat 3316-02-7

    ζ-Stat (NSC37044) is a specific and atypicalPKC-ζinhibitor, with an IC50 of 5μM. ζ-Stat can reduce melanoma cell lines proliferation and induce apoptosis, and has antitumor activity in vitro.

  • YN310151 Chelerythrine chloride 3895-92-9

    Chelerythrine is a potent, selective antagonist of PKC with IC50 of 0.66 mM.

  • YN310315 Decursin 5928-25-6

    Decursin ((+)-Decursin) is a cytotoxic agent and a potentprotein kinase Cactivator from the Root ofAngelica gigas. Decursin inhibits tumor growth, migration, and invasion in gastric cancer by down-regulating CXCR7 expression. ...

  • YN310199 N-Desmethyltamoxifen hydroch... 15917-65-4

    N-Desmethyltamoxifen hydrochloride is the major metabolite of tamoxifen in humans. N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potentprotein kinase C (PKC)inhibitor than Tamoxifen. N-Desmethyltamoxifen hydrochlo...

  • YN310308 Phorbol 12-myristate 13-aceta... 16561-29-8

    Phorbol 12-myristate 13-acetate (PMA), a phorbol ester, is a dualSphK and protein kinase C (PKC)activator. Phorbol 12-myristate 13-acetate induces differentiation in THP-1 cells.

  • YN310365 Desmethylglycitein 17817-31-1

    Desmethylglycitein (4',6,7-Trihydroxyisoflavone), a metabolite of daidzein, sourced fromGlycine maxwith antioxidant, and anti-cancer activities. Desmethylglycitein binds directly toCDK1 and CDK2in vivo, resulting in the suppres...

  • YN310093 DCP-LA 28399-31-7

    DCP-LA (FR236924), a linoleic acid derivative, selectively and directly activatesPKCε.

  • YN310349 Ingenol 30220-46-3

    Ingenol is a PKC activator, with a Ki of 30 μM, with antitumor activity.

  • YN310198 N-Desmethyltamoxifen 31750-48-8

    N-Desmethyltamoxifen is the major metabolite of tamoxifen in humans. N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potentprotein kinase C (PKC)inhibitor than Tamoxifen. N-Desmethyltamoxifen is also a potent regula...

  • YN310170 ζ-Stat trisodium 31894-34-5

    ζ-Stat trisodium (NSC37044 trisodium) is a specific and atypicalPKC-ζinhibitor, with an IC50 of 5μM. ζ-Stat trisodium can reduce melanoma cell lines proliferation and induce apoptosis, and has antitumor activity in vitr...

  • YN310357 Chelerythrine 34316-15-9

    Chelerythrine is a natural alkaloid, acts as a potent and selective Ca2+/phospholopid-dependentPKCantagonist, with an IC50 of 0.7μM. Chelerythrine has antitumor, antidiabetic and anti-inflammatory activity. Chelerythrine inhi...

  • YN310370 Cercosporin 35082-49-6

    Cercosporin is produced by a plant pathogen,Cercosporakikuchii, and theelsinochromes, pigments of the elsinoe family of fungi. Cercosporin is a potent photosensitizer with a short activation wavelength, mostly suitable for superficial ...

  • YN310316 Phorbol 12,13-dibutyrate 37558-16-0

    Phorbol 12,13-dibutyrate (Phorbol dibutyrate) is aPKCactivator and a potent skin tumor promoter.

  • YN310216 Ionomycin 56092-81-0

    Ionomycin (SQ23377) is a potent, selectivecalcium ionophore and an antibiotic produced byStreptomyces conglobatus. Ionomycin (SQ23377) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotesapoptos...

  • YN310244 Valrubicin 56124-62-0

    Valrubicin is a chemotherapy agent, inhibits TPA- and PDBu-inducedPKCactivation with IC50s of 0.85 and 1.25μM, respectively, and has antitumor and antiinflammatory activity.

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