Polyphyllin VI and polyphyllin VII possess anti-cancer activities, they exhibits strong inhibitory effects on lung cancer cell growth in vitro and in vivo by inducing G2/M cell cycle arrest and triggering apoptosis.
Ac-FLTD-CMK, a gasdermin D (GSDMD)-derived inhibitor, is a specificinflammatory caspasesinhibitor. Ac-FLTD-CMK is effective againstcaspases-1(IC50 of 46.7nM),caspases-4(IC50 of 1.49μM),caspases-5(IC50 of 329nM...
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