YN321793 Angiotensin II 5-valine 58-49-1

Angiotensin II 5-valine is an agonist ofangiotensin receptor.

YN320809 Angiotensin II human 4474-91-3

Angiotensin II human is converted by Angiotensin I through removal of two C-terminal residues by the enzyme angiotensin-converting enzyme (ACE). Angiotensin II is mediated by AT1 and AT2 receptors, which are seven transmembr...

YN321952 Angiotensin II (3-8), human 12676-15-2

Angiotensin II (3-8), human is a less effective agonist at theangiotensin AT1receptor.

YN320464 Angiotensin III 12687-51-3

Angiotensin III is anangiotensin 1 (AT1) and AT2receptor agonist.

YN321959 Angiotensin III, human, mo... 13602-53-4

Angiotensin III, human, mouse is a heptapeptide, acts as an endogenousangiotensin type 2 receptor (AT2R)agonist, with IC50s of 0.648nM and 21.1nM for AT2R and AT1R, respectively.

YN321976 Angiotensin II (5-8), human 34233-50-6

Angiotensin II (5-8), human is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II. Angiotensin II binds the AT II type 1 (AT1) receptor, stimulating GPCRs in vascular smooth muscle cells and ...

YN321964 [Sar1, Ile8]-Angiotensin I... 37827-06-8

[Sar1, Ile8]-Angiotensin II is a peptide that has multiple effects on vascular smooth muscle, including contraction of normal arteries and hypertrophy or hyperplasia of cultured cells or diseased vessels.

YN321981 Angiotensin I/II (1-6) 47896-63-9

Angiotensin I/II 1-6 contains the amino acids 1-6 and is converted from Angiotensin I/II peptide. Angiotensin I is formed by the action of renin on angiotensinogen. Angiotensin II is produced from angiotensin I. Angiotensin...

YN320589 Angiotensin (1-7) 51833-78-4

Angiotensin 1-7 (Ang-(1-7)) is a major active component of the renin-angiotensin system (RAS), produced from cleavage of Ang II by angiotensin-converting-enzyme type 2 (ACE2). Angiotensin 1-7 inhibits purified canine ACE act...

YN321978 Angiotensin II (1-4), human 52580-29-7

Angiotensin II (1-4), human is an endogenous peptide produced from AT I by angiotensin-converting-enzyme (ACE). Angiotensin II binds the AT II type 1 (AT1) receptor, stimulating GPCRs in vascular smooth muscle cells a...

YN321419 Tranilast 53902-12-8

Tranilast?is an antiallergic drug by inhibiting lipid mediator and cytokine release from inflammatory cells, used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.

YN321982 Angiotensin I/II (1-5) 58442-64-1

Angiotensin I/II 1-5 is a peptide that contains the amino acids 1-5, which is converted from Angiotensin I/II. Angiotensin I is formed by the action of renin on angiotensinogen. Angiotensin II is produced from angiotensin I. A...

YN320475 H-Val-Pro-Pro-OH 58872-39-2

H-Val-Pro-Pro-OH, a milk-derived proline peptides derivative, is an inhibitor of Angiotensin I converting enzyme(ACE), with an IC50 of 9μM.

YN320810 Angiotensin II human acetat... 68521-88-0

Angiotensin II (angII) is an octapeptide hormone which affects the activities of heart, kidney, vasculature and brain. It works via binding to specific receptors present on cell membranes.

YN321195 trans-Tranilast 70806-55-2

Trans-Tranilast is an antiallergic drug, used to treat bronchial asthma, allergic rhinitis and atopic dermatitis.

YN321420 Tranilast sodium 104931-56-8

Tranilast sodium (MK-341 sodium) acts as an anti-atopic agent. Tranilast suppresses production ofprostagl and in D2(PGD2,IC50= 0.1 mM). Tranilast sodium exhibits anti-inflammatory and immunomodulatory effects. Tranilast sodiu...

YN321156 Losartan 114798-26-4

Losartan D4 is the deuterium labeled Losartan. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.

YN320641 Losartan Carboxylic Acid 124750-92-1

Losartan Carboxylic Acid (E-3174, EXP-3174), an active carboxylic acid metabolite of Losartan, is a non-peptide angiotensin II (AT1) receptor antagonist. Losartan Carboxylic Acid inhibits the specific binding of [125I]-angio...

YN321157 Losartan potassium 124750-99-8

Losartan is an angiotensin II receptor antagonist, competes with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.

YN320590 CGP-42112 127060-75-7

CGP-42112 (CGP-42112A) is a potent Angiotensin-II subtype 2 receptor(AT2 R) agonist.