Chemical structure
Cat.No.
Product Name
CAS no.
Target
YN430061 SNIPER(BRD)-1 2095244-54-3
SNIPER(BRD)-1, consists of an IAP antagonist LCL-161 derivative and a BET inhibitor, (+)-JQ-1, connected by a linker. SNIPER(BRD)-1 induces the degradation ofBRD4via the ubiquitin-proteasome pathway. SNI...
YN430060 SNIPER(ABL)-033 2222354-18-7
SNIPER(ABL)-033, conjugating HG-7-85-01 (ABL inhibitor) to LCL161 derivative (IAP lig and ) with a linker, induces the reduction of BCR-ABL protein with a DC50of 0.3μM.
SNIPER(BRD)-1, consists of an IAP antagonist LCL-161 derivative and a BET inhibitor, (+)-JQ-1, connected by a linker. SNIPER(BRD)-1 induces the degradation ofBRD4via the ubiquitin-proteasome pathway. SNI...
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