Chemical structure
Cat.No.
Product Name
CAS no.
Target
YN420297 α-Linolenic acid 463-40-1
α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation ofPI3K/Aktsignaling. α-Linolenic acid possess...
YN420290 Cyclovirobuxine D 860-79-7
Cyclovirobuxine D (CVB-D) is the main active component of the traditional Chinese medicineBuxus microphylla. Cyclovirobuxine D inducesautophagy and attenuates the phosphorylation of Akt and mTOR. Cyclovirobuxine D inhibits ...
YN420288 Sophocarpine 6483-15-4
Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.
NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line
3CAI is a potent and specificAKT1 and AKT2inhibitor.
YN420215 Triciribine 35943-35-2
Triciribine is a DNA synthesis inhibitor, also inhibits Akt in PC3 cell line and HIV-1 in CEM-SS, H9, H9IIIB, U1 cells with IC50 of 130 nM and 20 nM, respectively does not inhibit PI3K/PDK1 5000-fold less act...
YN420069 (Z)-Guggulsterone 39025-23-5
Z-guggulsterone, a constituent of Indian Ayurvedic medicinal plantCommiphora mukul, inhibits the growth of human prostate cancer cells by causingapoptosis. Z-guggulsterone inhibits angiogenesis by suppressing theVEGF–VEGF-R2–...
YN420179 Miltefosine 58066-85-6
Miltefosine inhibits PI3K/Akt activity with ED50 of 17.2 μM and 8.1 μM in carcinoma cell lines A431 and HeLa, first oral drug for Visceral leishmaniasis, effective against both promastigotes and amastigotes.
YN420282 Artemisinin 63968-64-9
Artemisinin is a sesquiterpene endoperoxide which is a potent antimalarial agent.
YN420304 Glaucocalyxin A 79498-31-0
Glaucocalyxin A, an ent-kauranoid diterpene fromRabdosia japonicavar., induces apoptosis in osteosarcoma by inhibiting nuclear translocation of Five-zinc finger Glis 1 (GLI1) via regulatingPI3K/Aktsignaling pathway. Glaucocalyx...
YN420314 Hederacolchiside A1 106577-39-3
Hederacolchiside A1, isolated fromPulsatilla chinensis, suppresses proliferation of tumor cells by inducing apoptosis through modulatingPI3K/Akt/mTORsignaling pathway. Hederacolchiside A1 hasantischistosomalactivity, affecting ...
YN420302 Loureirin A 119425-89-7
Loureirin A is a flavonoid extracted from the red resin of the herbs of Dracaena cochinchinensis, which is known as Dragon's Blood. Loureirin A inhibits platelet activation by an impairment of PI3K/Akt signaling. Loureirin A in...
YN420239 Solenopsin 137038-57-4
Solenopsin is an ATP-competitiveAKTinhibitor with IC50 value of 10μM .
YN420289 Sophocarpine monohydrate 145572-44-7
Sophocarpine and matrine exert anti-cachectic effects probably through inhibition of TNF-alpha and IL-6 and prevent cachexia-related symptoms induced by colon26 adenocarcinoma in mice. Sophocarpine injection (called the Kangke inj...
YN420278 Perifosine 157716-52-4
Perifosine (KRX-0401) is a novel Akt inhibitor with IC50 of 4.7 μM in MM.1S cells, targets pleckstrin homology domain of Akt. Phase 3.
YN420321 Crosstide 171783-05-4
Crosstide is a peptide analog of glycogen synthase kinase α/β fusion protein sequence which is a substrate forAkt.
SC79 is a brain-penetrable Akt phosphorylation activator and an inhibitor of Akt-PH domain translocation.
TELL : +86-020-82000279
Add:Room 519, Block F, Guangzhou International Business Incubator, No.3 Lanyue Road, Science Town, Huangpu District, Guangzhou, China.