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Factor Xa

Chemical structure

Cat.No.

Product Name

CAS no.

Target

  • YN372791 Gabexate mesylate 56974-61-9

    Gabexate Mesylate is a serine protease inhibitor with IC50 of 0.19 μM which is used therapeutically in the treatment of pancreatitis and disseminated intravascular coagulation.

  • YN372829 Fondaparinux sodium 114870-03-0

    Fondaparinux sodium is an antithrombin-dependentfactor Xainhibitor.

  • YN372660 Otamixaban 193153-04-7

    Otamixaban(FXV673) is a potent (Ki = 0.5nM), selective, rapid acting, competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa. Otamixaban is a potent (Ki = 0.5nM), selective,...

  • YN372544 RWJ-445167 226566-43-4

    RWJ-445167 (3DP-10017) is a dual inhibitor ofthrombin and factor Xawith Kiof 4.0nM and 230nM, respectively, exhibiting potent antithrombotic activity.

  • YN370247 Betrixaban 330942-05-7

    Betrixaban is a highly potent, selective, and orally efficacious factor Xa (fXa) inhibitor

  • YN372646 Rivaroxaban 366789-02-8

    Rivaroxaban is a direct inhibitor of Factor Xa with Ki and IC50 of 0.4 nM and 0.7 nM in cell-free assays, respectively. It is selective for human factor Xa, for which it has >10 000-fold greater selectivity than for other biologic...

  • YN370245 Edoxaban 480449-70-5

    Edoxaban (DU-176b, Savaysa), an antithrombotic agent, is a selective, potent and orally active inhibitor of factor Xa (FXa) with Ki of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively.

  • YN372637 Apixaban 503612-47-3

    Apixaban is a highly selective, reversible inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively.

  • YN372684 5-R-Rivaroxaban 865479-71-6

    5-R-Rivaroxaban is (R)-enantiomer of Rivaroxaban. Rivaroxaban (BAY 59-7939) is a highly potent and selective, directFactor Xa(FXa) inhibitor, achieving a strong gain in anti-FXa potency (IC500.7nM;Ki0.4nM).

  • YN370246 Edoxaban tosylate monohydrate 1229194-11-9

    Edoxaban is a selective factor Xa inhibitor with Ki of 0.561 nM, >10 000-fold selectivity over thrombin and FIXa, and is also an orally bioavailable anticoagulant drug.

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