Pronethalol ((±)-Pronethalo) is a non-selectiveβ-adrenergicantagonist. Pronethalol is a potent inhibitor ofSox2expression. Pronethalol protects against and to reverse Digitalis-induced ventricular arrhythmias, and limits the cer...
Norepinephrine tartrate (Levarterenol tartrate), a naturally occurring chemical in the body that acts as both a stress hormone and neurotransmitter, is aβ1-selectiveadrenergic receptoragonist withEC50of 5.37μM.
(−)-Norepinephrine is a natural neurotransmitter and hormone. It is an agonist of adrenergic receptors with Ki values of 330, 56, and 740 nM for α1, α2, and β1 adrenoceptors, respectively.
Tyramine is a naturally occurring trace amine derived from the amino acid tyrosine and acts as a catecholamine releasing agent.
Norethindrone acetate (19-Norethindrone acetate, NA) is a common synthetic hormone used in oral contraceptives. Norethindrone acetate is a well-tolerated, effective option to manage pain and bleeding for all stages of endometriosis.
Aldosterone is the primary mineralocorticoid. Aldosterone is a steroid hormone, and it is synthesized and secreted in response to renin-angiotensin system activation (RAS) or high dietary potassium by the zona glomerulosa (ZG) of...
Pronethalol ((±)-Pronethalo) is a non-selectiveβ-adrenergicantagonist. Pronethalol is a potent inhibitor ofSox2expression. Pronethalol protects against and to reverse Digitalis-induced ventricular arrhythmias and limits the cere...
Vanillylm and elic acid is the endproduct of epinephrine and norepinephrine metabolism. Vanillylm and elic acid can be used as an indication of the disorder in neurotransmitter metabolism as well. Vanillylm and elic acid hasantioxidant...
Quinidine is an antiarrhythmic agent for the treatment of abnormal heart rhythms and also malaria.
Felypressin-Acetate is a non-catecholamine vasoconstrictor that is chemically associated to vasopressin, the posterior pituitary hormone.
Glycerol is a clear, colourless, viscous, sweet-tasting liquid. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis.
L-Cystathionine is a nonprotein thioether and is a key amino acid associated with the metabolic state of sulfur-containing amino acids. L-Cystathionine protects against Homocysteine-induced mitochondria-dependent apoptosis of vascula...
Palmitic acid is the most common saturated fatty acid found in animals, plants and microorganisms with anti-tumor activity.
Urea is a highly soluble organic compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.
Progesterone is an endogenous steroid hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. A potent agonist of the nuclear progesterone receptor (nPR) with Kd of 1 nM An agonist of the me...
Dipyridamole (Persantine) is a phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells.
Bradykinin is a potent vasodilator peptide that exerts its vasodilatory action through stimulation of specific endothelial B2 receptors, thereby causing the release of prostacyclin, NO, and EDHF.
Hydrochlorothiazide (HCTZ), an orally active diuretic drug of the thiazide class, inhibits transformingTGF-β/Smadsignaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of thecalcium-activated pota...
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