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CXCR

Chemical structure

Cat.No.

Product Name

CAS no.

Target

  • YN320142 Nicotinamide N-oxide 1986-81-8

    Nicotinamide N-oxide, anin vivonicotinamide metabolite, is a potent, and selective antagonist of theCXCR2receptor.

  • YN320226 MSX-130 4051-59-6

    MSX-130 is aCXCR4antagonist. MSX-130 inhibits cancer metastasis.

  • YN320224 MSX-127 6616-56-4

    MSX-127 is a CXCR4 antagonist. MSX-127 inhibits cancer metastasis.

  • YN321755 Corydalmine 30413-84-4

    Corydalmine (L-Corydalmine), an alkaloid isolated from roots ofCorydalis Chaerophylla, inhibits spore germination of some plant pathogenic as well as saprophytic fungi. Corydalmine acts as an oral analgesic agent, exhibiting potent an...

  • YN320997 WZ811 55778-02-4

    WZ811 is a highly potent competitive CXCR4 antagonist with EC50 of 0.3 nM.

  • YN320048 Plerixafor 110078-46-1

    Plerixafor (AMD3100) is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM in cell-free assays, respectively.

  • YN321703 Baohuoside I 113558-15-9

    Baohuoside I (also known as Icariside II) is a flavonoid isolated from Epimedium koreanum Nakai with anti-inflammatory and anti-cancer activities. It may exert cytotoxic effect via the ROS/MAPK pathway.

  • YN320609 Antileukinate 138559-60-1

    Antileukinate, a hexapeptide, is a potent inhibitor ofCXC-chemokine receptor (CXCR). Antileukinate inhibits neutrophil chemotaxis and activation. Antileukinate can be used for the research of acute inflammation and injury .

  • YN322004 ALX 40-4C 143413-49-4

    ALX 40-4C is a small peptide inhibitor of thechemokine receptor CXCR4, inhibits SDF-1 from binding CXCR4 with a Ki of 1μM, and suppresses the replication of X4 strains of HIV-1; ALX 40-4C Trifluoroacetate also a...

  • YN321289 Plerixafor octahydrochloride 155148-31-5

    Plerixafor 8HCl (AMD3100 8HCl) is the hydrochloride of Plerixafor, a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM in cell-free assays, respectively.

  • YN321083 SB225002 182498-32-4

    SB225002 is a potent, and selective CXCR2 antagonist with IC50 of 22 nM for inhibiting interleukin IL-8 binding to CXCR2, > 150-fold selectivity over the other 7-TMRs tested.

  • YN321050 AMD 3465 hexahydrobromide 185991-07-5

    AMD 3465 hexahydrobromide (GENZ-644494 hexahydrobromide) is a potent antagonist ofCXCR4, inhibits binding of 12G5 mAb and CXCL12AF647toCXCR4, with IC50s of 0.75nM and 18nM in SupT1 cells; AMD 3465 also po...

  • YN321051 AMD 3465 185991-24-6

    AMD 3465 (GENZ-644494) is a potent antagonist ofCXCR4, inhibits binding of 12G5 mAb and CXCL12AF647toCXCR4, with IC50s of 0.75nM and 18nM in SupT1 cells; AMD 3465 also potently inhibits the replication of...

  • YN321282 SB-265610 211096-49-0

    SB-265610 is a selective, competitive, nonpeptide and allostericCXCR2antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization and neutrophil chemotaxis with IC50s...

  • YN320950 Reparixin 266359-83-5

    Reparixin(Repertaxin) is a inhibitor of human CXCR1/R2 and rat CXCR2 receptor activation. It also inhibits human CXCL8 receptor activation.

  • YN320951 Reparixin L-lysine salt 266359-93-7

    Reparixin L-lysine salt is an allosteric inhibitor ofchemokine receptor 1/2 (CXCR1/2)activation.

  • YN320962 AMG 487 473719-41-4

    AMG 487 is an orally active and selective CXC chemokine receptor 3 (CXCR3) antagonist that inhibits the binding of IP-10 (CXCL10) and ITAC (CXCL11) to CXCR3 with IC50 of 8.0 nM and 8.2 nM, respectively...

  • YN320963 AMG 487 (S-enantiomer) 473720-30-8

    AMG 487 S-enantiomer is the S enantiomer of AMG 487. AMG 487 is an antagonist of the chemokine receptorCXCR3.

  • YN320210 Navarixin 473727-83-2

    SCH-527123 is a potent, orally bioavailable CXCR2/CXCR1 antagonist with IC50 values of 2.6 nM and 36 nM, respectively.

  • YN320003 SCH 563705 473728-58-4

    SCH 563705 is a potent and orally availableCXCR2 and CXCR1antagonist, with IC50s of 1.3nM, 7.3nM and Kis of 1 and 3nM, respectively.

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