YN321129 Strontium Ranelate 135459-87-9

Strontium Ranelate (S12911) is an antiosteoporotic agent that acts by reducing bone resorption and promoting bone formation, thereby inducing a positive bone balance. Strontium Ranelate also can activate thecalcium-sensing receptor (...

YN320175 Tecalcet Hydrochloride 177172-49-5

Tecalcet Hydrochloride (R 568 Hydrochloride), an orally active calcimimetic compound, allosterically and positively modulates thecalcium-sensing receptor (CaSR). Tecalcet Hydrochloride (R 568 Hydrochloride) increases the sensit...

YN321292 Cinacalcet 226256-56-0

Cinacalcet (AMG073, Sensipar, Cin) is an orally active, allosteric agonist of receptors for calcium (CaR) that increases the sensitivity of the CaR to Ca.

YN321722 Ligustroflavone 260413-62-5

Ligustroflavone, isolated from the leaves of Turpinia montana, shows high antioxidant capacity and is reported to be an AMPK activator.

YN320001 NPS-2143 284035-33-2

NPS-2143 is a novel potent and selective antagonist of Ca(2+) receptor with IC50 of 43 nM.

YN320185 NPS-2143 hydrochloride 324523-20-8

NPS-2143 hydrochloride (SB-262470A hydrochloride), an orally active calcilytic agent, is a selective and potentcalcium ion-sensing receptor (CaSR)antagonist. NPS-2143 hydrochloride (SB-262470A hydrochloride) blocks increase...

YN321293 Cinacalcet hydrochloride 364782-34-3

Cinacalcet HCl represents a new class of compounds for the treatment of hyperparathyroidism.

YN321284 Calcium-Sensing Receptor A... 478963-79-0

Calcium-Sensing Receptor Antagonists I is an antagonist of calcium-sensing parathyroid hormone receptors.

YN321168 Evocalcet 870964-67-3

Evocalcet has an activating effect oncalcium sensing receptor(CaSR) extracted from patent WO 2017061621 A1, compound A.

YN321988 Etelcalcetide hydrochloride 1334237-71-6

Etelcalcetide hydrochloride (AMG 416 hydrochloride) is a synthetic peptide as an activator of thecalcium sensing receptor (CaSR). Etelcalcetide hydrochloride is effective in lowering parathyroid hormone (PTH) concentrations in ...

YN320253 Calhex 231 hydrochloride 2387505-78-2

Calhex 231 hydrochloride is aCaSRinhibitor via negative allosteric modulation. Calhex 231 hydrochloride blocks Ca2+-induced accumulation of [3H]inositol phosphate with an IC50 of 0.39μM in HEK293 cells. Calhex 231 hydrochlori...