Chemical structure
Cat.No.
Product Name
CAS no.
Target
YN440449 DDR1-IN-2 1429617-90-2
DDR1-IN-2 is a potent inhibitor ofdiscoidin domain receptor 1(DDR1), with an IC50 of 13.1nM, and also less potently inhibits DDR2, with an IC50 of 203nM.
YN440303 DDR1-IN-1 1449685-96-4
DDR1-IN-1 is a potent and selective discoidin domain receptor 1 (DDR1) receptor tyrosine kinase inhibitor with IC50 of 105 nM, about 3-fold selectivity over DDR2.
YN440451 DDR Inhibitor 1644069-80-6
DDR Inhibitor is a potentdiscoidin domain receptor (DDR)inhibitor, with an IC50 of 3.3nM for DDR2, and shows 53% inhibition on DDR1 at 1.5nM.
WRG-28 is a selective, extracellularly actingDDR2allosteric inhibitor with an IC50 of 230nM. WRG-28 uniquely inhibits receptor-lig and interactions via allosteric modulation of the receptor. WRG-28 inhibits tumor invasion a...
YN440166 FGFR1/DDR2 inhibitor 1 2308497-58-5
FGFR1/DDR2 inhibitor 1 is an orally active inhibitor offibroblast growth factor receptor 1 (FGFR1) and discoindin domain receptor 2 (DDR2), with IC50 values of 31.1nM and 3.2nM, respectively. Antitumor activity.
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