Brilliant Black BN
Brilliant black BN (E151) is an azodye and a food colorant. Brilliant black BN is a promisingantiviral agentagainstEV71infection via inhibiting the interaction between EV71 and its cellular uncoating factor cyclophilin A. Br...
EIDD-1931 (Beta-d-N4-hydroxycytidine; NHC) is a novel nucleoside analog and behaves as a potentanti-virus agent. EIDD-1931 effectively inhibits the replication activity ofvenezuelan equine encephalitisvirus (VEEV),Chiku...
Norwogonin, isolated fromScutellaria baicalensisGeorgi, possesses antiviral activity againstEnterovirus 71 (EV71)with an IC50 of 31.83 μg/ml
Lanatoside C, a cardiac glycoside which belongs to a class of compounds derived from plants called foxglove, possesses the ability to inhibit the interchange of Na+ and K+ across cell membrane and is widely used to treat anti-arrhythmia...
Hederasaponin B, isolated fromHedera helix, has broad-spectrumantiviralactivity against various subgenotypes of Enterovirus 71 (EV71).
Pirodavir is a potent, broad-spectrum picornavirus inhibitor, and is highly active against both group A and group Brhinovirusserotypes. Pirodavir is very potent in a virus yield reduction assay (IC90=2.3nM).
Pocapavir (SCH-48973;V-073), a capsid inhibitor, preventing virion uncoating upon entry into the cell. Pocapavir has antiviral activity against polioviruses. Pocapavir also inhibitsenterovirusinfections.
Pleconaril is a capsid inhibitor used previously to treat enterovirus infections. Pleconaril is effective in inhibiting replication with IC50 of < 0.050 μM.
Rupintrivirvr (AG7088), an antiviral drug, is a potent, selective and irreversible inhibitor ofhuman rhinovirus (HRV) 3C protease. Rupintrivirvr inhibits replication of a panel of 48 different HRV serotypes in H1-HeLA and...
LY2334737 is an nucleoside analog and is an orally active prodrug of Gemcitabine. LY2334737 exhibits inhibitory activity againstenterovirus A71 (EV-A71)infection. LY2334737 has antiviral and anticancer effects.
TTP-8307 is a potent inhibitor of the replication of severalrhino- and enteroviruses. TTP-8307 inhibits coxsackievirus B3 (CVB3; EC50=1.2μM) and poliovirus by interfering with the synthesis ofviral RNA. TTP-8307 exer...
Vapendavir diphosphate (BTA798 diphosphate) is a potententeroviralcapsid binder (CB). Vapendavir diphosphate (BTA798 diphosphate) possesses potent antiviral activity for enterovirus 71 (EV71) replication, withEC50values of 0.5...
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