YN380193 Deferoxamine mesylate 138-14-7

Deferoxamine mesylate is the mesylate salt of Deferoxamine, which forms iron complexes and is used as a chelating agent.

YN380219 Rutin 153-18-4

Rutin, a flavonol glycoside found in many plants including buckwheat tobacco forsythia hydrangea viola, etc., which possesses healthy effects for human.

YN380102 Tramiprosate 3687-18-1

Homotaurine is a synthetic organic compound that has GABAergic activity by mimicking GABA. It is a GABAA partial agonist as well as a GABAB receptor partial agonist with low efficacy.

YN380225 Saikosaponin C 20736-08-7

Saikosaponin C is a bioactive component found inradix bupleuri, targetsamyloid beta and tauin Alzheimer's disease. Saikosaponin C inhibits the secretion of both Aβ1-40 and Aβ1-42, and suppresses abnormal tau phosphorylation, bu...

YN380217 Ginsenoside Rg1 22427-39-0

Ginsenoside Rg1, identified as a protopanaxatriol-type, has pharmacological actions such as neuroprotective and anti-tumor effects on various cancer types.

YN380111 Hoechst 34580 23555-00-2

Hoechst 34580 (HOE 34580) is a cell-permeable blue fluorescent dye to stain DNA and nuclei. Hoechst 34580 is also a good candidate for treating the Alzheimer's disease by inhibiting amyloid beta (Aβ) formation with IC50 ...

YN380216 Geniposide 24512-63-8

Geniposide is an iridoid glycoside isolated from the fruit of Gardenia jasminoides Ellis.

YN380251 Dihydroergocristine mesylate 24730-10-7

Dihydroergocristine mesylate (DHEC mesylate) is a inhibitor of γ-secretase (GSI), reduces the production of the Alzheimer's diseaseamyloid-βpeptides, binds directly to γ-secretase and Nicastrin with equilibrium dissociation c...

YN380107 Frentizole 26130-02-9

Frentizole is a novel inhibitor of amyloid beta peptide (Abeta) binding alcohol dehydrogenase (ABAD) interaction with IC50 of 200 μM. Frentizole is a nontoxic antiviral and immunosuppressive agent used clinically in rheuma...

YN380231 Ginsenoside Rg2 52286-74-5

(20S)Ginsenoside Rg2, a constituent existing in red ginseng, has been reported to exert strong inhibitory action on various cancer cells.

YN380233 Schisantherin B 58546-55-7

Schisantherin B (Gomisin-B; Wuweizi ester-B; Schisantherin-B) is a natural product.

YN380227 Licochalcone B 58749-23-8

Licochalcone B is an extract from the root ofGlycyrrhiza inflate. Licochalcone B inhibitsamyloid β(Aβ42) self-aggregation (IC50=2.16μM) and disaggregate pre-formed Aβ42 fibrils, reduce metal-induced Aβ42 aggregation throug...

YN380232 Notoginsenoside R1 80418-24-2

Notoginsenoside R1 is the main ingredient with cardiovascular activity in Panax notoginseng. It inhibits TNF-α-induced PAI-1 overexpression via extracellular signal-related kinases (ERK1/2) and phosphatidylinositol 3-kinase (P...

YN380129 ARN2966 102212-26-0

ARN2966 is a potent post-transcriptional modulator of APP expression; reduces expression of APP with resultant lower production of Aβ. This potent post-transcriptional modulation of APP expression differs from other mechanis...

YN380284 β-amyloid (12-28) 107015-83-8

β-amyloid (12-28) is a peptide fragment of β-amyloid protein (β1-42). β1–42 a 42 amino acid protein , is the major component of senile plaque cores. β-amyloid (12-28) shows aggregation properties. β-amyloid (12-28) has the potential ...

YN380289 β-Amyloid (1-42), human TF... 107761-42-2

β-Amyloid (1-42), human TFA (Amyloid β-Peptide (1-42) (human) TFA) is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease.

YN380293 β-Amyloid (1-28) 109770-29-8

β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding. Beta-amyloid is a peptide that forms amyloid plaques in the brains of Alzheimer's disease (AD) patients.

YN380305 β-Amyloid (18-28) 112163-49-2

β-Amyloid (18-28) is a peptide fragment of β-Amyloid.

YN380242 Semilicoisoflavone B 129280-33-7

Semilicoisoflavone B, an isoflavone, mainly derived fromGlycyrrhiza uralensisFisch.. Semilicoisoflavone B reducesamyloid β(Aβ) secretion by inhibiting β-secretase-1 (BACE1) expression and activity. Semilicoisoflavone B dec...

YN380281 β-Amyloid (1-40) 131438-79-4

β-Amyloid (1-40) is a primary protein in plaques found in the brains of patients with Alzheimer's disease.