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HIV Protease

Chemical structure


Product Name

CAS no.


  • YN373368 Cytochalasin A 14110-64-6

    Cytochalasin A is a cell-permeable fungal toxin that is an oxidized derivative of cytochalasin B. Cytochalasin A is an inhibitor ofHIV-1 protease(IC50=3μM) and inhibits actin polymerization and interferes with microtubule as...

  • YN373431 Pepstatin 26305-03-3

    Pepstatin A is a potent aspartic protease inhibitor, and also inhibits HIV replication.

  • YN373234 Ganoderic acid B 81907-61-1

    Ganoderic acid B is a triterpene isolated from a mushroomGanoderma lucidum. Ganoderic acid B inhibits the activation of Epstein-Barr virus (EBV) antigens as telomerase inhibitor. Ganoderic acid B is a moderately active inhibitor...

  • YN373301 Rosamultin 88515-58-6

    Rosamultin is a 19 α-hydroxyursane-type triterpenoid isolated from Potentilla anserina L. that inhibits HIV-1 protease. Rosamultin has protective effects on H2O2-induced oxidative damage and apoptosis.

  • YN373309 Ganodermanondiol 107900-76-5

    Ganodermanondiol is a melanogenesis inhibitor isolated from theGanoderma lucidum.Ganodermanondiol exhibits potent cytoprotective effects on tert-butyl hydroperoxide-induced hepatotoxicity. Ganodermanondiol shows significant anti-HIV-...

  • YN373132 Escin IA 123748-68-5

    Escin IA is a triterpene saponin isolated from horse chestnut, which inhibitsHIV-1 proteasewith IC50 values of 35μM. Escin IA has anti-TNBC metastasis activity, and its action mechanisms involved inhibition of epithelial-...

  • YN372423 Saquinavir 127779-20-8

    Saquinavir (Ro 31-8959) is a potent and selective inhibitor of HIV proteinase with a mean IC50 of 2.7 nM in JM cells.

  • YN373989 L-689502 138483-63-3

    L-689502 is a potent inhibitor ofHIV-l proteasewith an IC50 of 1nM.

  • YN372422 Saquinavir Mesylate 149845-06-7

    Saquinavir mesylate is an HIV Protease Inhibitor used in antiretroviral therap Saquinavir is a protease inhibitor. Proteases are enzymes that cleave protein molecules into smaller fragments. HIV protease is vital for both viral r...

  • YN372840 Indinavir 150378-17-9

    Indinavir(MK-639; L735524) is a potent and specific HIV protease inhibitor that appears to have good oral bioavailability.

  • YN372698 Ritonavir 155213-67-5

    Ritonavir is a Cytochrome P450 3A and Protease Inhibitor Also inhibits Cytochrome P450 2D6, P-Glycoprotein and induces Cytochrome P450 2C19, Cytochrome P450 1A2, Cytochrome P450 2C9, Cytochrome P450 2B6 and UDP G...

  • YN372841 Indinavir sulfate 157810-81-6

    Indinavir sulfate is a specific and potent inhibitor of HIV-1 protease and is widely used in the treatment of AIDS.

  • YN372278 Nelfinavir 159989-64-7

    Nelfinavir (AG-1341) is a potent and orally bioavailableHIV-1 proteaseinhibitor (Ki=2nM) for HIV infection. Nelfinavir is a broad-spectrum, anticancer agent .

  • YN372279 Nelfinavir Mesylate 159989-65-8

    Nelfinavir Mesylate is a potent HIV protease inhibitor with Ki of 2 nM.

  • YN372436 Amprenavir 161814-49-9

    Amprenavir is a potent PXR-selective agonist, and an HIV protease inhibitor, used to treat HIV.

  • YN372531 PNU-103017 166335-18-8

    PNU-103017 is anHIV proteaseinhibitor.

  • YN372261 Tipranavir 174484-41-4

    Tipranavir (PNU-140690) inhibits the enzymatic activity and dimerization ofHIV-1 protease, exerts potent activity against multi-protease inhibitor (PI)-resistant HIV-1 isolates with IC50s of 66-410nM.

  • YN372211 Lopinavir 192725-17-0

    Lopinavir is a potent HIV protease inhibitor with Ki of 1.3 pM in a cell-free assay.

  • YN371766 Lopinavir Metabolite M-1 192725-39-6

    Lopinavir Metabolite M-1, an active metabolite of Lopinavir, inhibitsHIV proteasewith a Ki of 0.7 pM. Lopinavir Metabolite M-1 has antiviral activities in vitro.

  • YN372425 Darunavir 206361-99-1

    Darunavir is a nonpeptidic HIV protease inhibitor, used to treat HIV infection.


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