Chemical structure
Cat.No.
Product Name
CAS no.
Target
YN321005 AR 231453 733750-99-7
AR 231453 is a potent, specific and orally availableGPR119agonist. AR 231453 can stimulate β-cell replication and improve islet graft function s.
APD668 is a potent GPR119 agonist with EC50s of 2.7 and 33 nM for human and rat forms, respectively.
YN321077 PSN632408 857652-30-3
PSN632408, a selective, orally activeGPR119agonist, shows similar potency to OEA at both recombinant mouse and human GPR119 receptors (EC50=5.6 and 7.9 uM, respectively). PSN632408 can stimulate β-cell replication an...
APD-597 (JNJ-38431055) is a potent and selective G protein-coupled receptor 119 (GPR119) agonist with EC50 of 46 nM for hGPR119 and an inhibitor of Cytochrome P450 2C9 (CYP2C9) with IC50 of 5.8 μM. A...
YN320537 GSK1292263 1032823-75-8
GSK1292263 is a novel GPR119 agonist, showing potential for the treatment of type 2 diabetes. Phase 2.
YN320961 MBX-2982 1037792-44-1
MBX-2982 is a selective, orally-available G protein-coupled receptor 119 (GPR119) agonist.
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