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HCV Protease

Chemical structure

Cat.No.

Product Name

CAS no.

Target

  • YN373422 Isoeuphorbetin 50886-61-8

    Isoeuphorbetin, a dimeric coumarin isolated fromViola philippica, is a potentHCV proteaseinhibitor with an IC50 of 3.63 µg/mL.

  • YN373946 Hepatitis Virus C NS3 Pr... 208939-95-1

    Hepatitis Virus C NS3 Protease Inhibitor 2 is a product-based peptide inhibitor ofhepatitis C virus (HCV) NS3 protease, with a Ki of 41nM.

  • YN370242 Boceprevir 394730-60-0

    Boceprevir is an oral, direct acting hepatitis C virus (HCV) protease inhibitor with Ki value of 14 nM for NS3. It is used in combination with other antiviral agents in the treatment of chronic hepatitis C, genotype 1.

  • YN370241 Telaprevir 402957-28-2

    Telaprevir (VX-950) is an HCV NS3-4A serine protease inhibitor with IC50 of 0.35 μM.

  • YN372204 Asunaprevir 630420-16-5

    Asunaprevir is an orally bioavailable inhibitor of the hepatitis C virus enzyme serine protease NS3 that is necessary for protein processing required for viral replication.

  • YN370243 Danoprevir 850876-88-9

    Danoprevir(ITMN-191) is a peptidomimetic inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50 of 0.2-3.5 nM, inhibition effect for HCV genotypes 1A/1B/4/5/6 is ~10-fold higher than 2B/3A. Phase 2.

  • YN370254 Narlaprevir 865466-24-6

    Narlaprevir is a potent, selective, orally bioavailable NS3 protease inhibitor(Ki=6nM; EC90=40nM)

  • YN370244 Simeprevir 923604-59-5

    Simeprevir (TMC435) is an oral and potentHCV NS3/4A proteaseinhibitor with a Ki of 0.36nM, and inhibits HCV replication with an EC50 of 7.8nM.

  • YN372282 Grazoprevir potassium salt 1206524-86-8

    Grazoprevir potassium salt (MK-5172 potassium salt) is a selective inhibitor ofHepatitis C virus NS3/4aprotease with broad activity across genotypes and resistant variants, with Kis of 0.01nM (gt1b), 0.01nM (gt1a), 0.08nM (gt2a...

  • YN371040 Paritaprevir 1216941-48-8

    Paritaprevir (ABT-450) is a nonstructural (NS) protein 3/4A protease inhibitor.

  • YN372281 Grazoprevir 1350514-68-9

    Grazoprevir anhydrous is a Hepatitis C Virus NS3/4A Protease inhibitor with IC50 values of 7pM, 4pM, and 62pM for HCV genotype 1a, 1B, and 4 respectively.

  • YN372463 Glecaprevir 1365970-03-1

    Glecaprevir is a hepatitis C virus (HCV) nonstructural (NS) protein 3/4A protease inhibitor that targets the the viral RNA replication. It displays IC50 values ranging from 3.5 to 11.3 nM for clinical isolates of HCV geno...

  • YN372283 Grazoprevir sodium salt 1425038-27-2

    Grazoprevir sodium salt (MK-5172 sodium salt) is a selective inhibitor ofHepatitis C virus NS3/4aprotease with broad activity across genotypes and resistant variants, with Kis of 0.01nM (gt1b), 0.01nM (gt1a), 0.08nM (gt2a), 0.1...

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