Chemical structure
Cat.No.
Product Name
CAS no.
Target
YN373422 Isoeuphorbetin 50886-61-8
Isoeuphorbetin, a dimeric coumarin isolated fromViola philippica, is a potentHCV proteaseinhibitor with an IC50 of 3.63 µg/mL.
YN373946 Hepatitis Virus C NS3 Pr... 208939-95-1
Hepatitis Virus C NS3 Protease Inhibitor 2 is a product-based peptide inhibitor ofhepatitis C virus (HCV) NS3 protease, with a Ki of 41nM.
YN370242 Boceprevir 394730-60-0
Boceprevir is an oral, direct acting hepatitis C virus (HCV) protease inhibitor with Ki value of 14 nM for NS3. It is used in combination with other antiviral agents in the treatment of chronic hepatitis C, genotype 1.
YN370241 Telaprevir 402957-28-2
Telaprevir (VX-950) is an HCV NS3-4A serine protease inhibitor with IC50 of 0.35 μM.
YN372204 Asunaprevir 630420-16-5
Asunaprevir is an orally bioavailable inhibitor of the hepatitis C virus enzyme serine protease NS3 that is necessary for protein processing required for viral replication.
YN370243 Danoprevir 850876-88-9
Danoprevir(ITMN-191) is a peptidomimetic inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50 of 0.2-3.5 nM, inhibition effect for HCV genotypes 1A/1B/4/5/6 is ~10-fold higher than 2B/3A. Phase 2.
YN370254 Narlaprevir 865466-24-6
Narlaprevir is a potent, selective, orally bioavailable NS3 protease inhibitor(Ki=6nM; EC90=40nM)
YN370244 Simeprevir 923604-59-5
Simeprevir (TMC435) is an oral and potentHCV NS3/4A proteaseinhibitor with a Ki of 0.36nM, and inhibits HCV replication with an EC50 of 7.8nM.
YN372282 Grazoprevir potassium salt 1206524-86-8
Grazoprevir potassium salt (MK-5172 potassium salt) is a selective inhibitor ofHepatitis C virus NS3/4aprotease with broad activity across genotypes and resistant variants, with Kis of 0.01nM (gt1b), 0.01nM (gt1a), 0.08nM (gt2a...
YN371040 Paritaprevir 1216941-48-8
Paritaprevir (ABT-450) is a nonstructural (NS) protein 3/4A protease inhibitor.
YN372281 Grazoprevir 1350514-68-9
Grazoprevir anhydrous is a Hepatitis C Virus NS3/4A Protease inhibitor with IC50 values of 7pM, 4pM, and 62pM for HCV genotype 1a, 1B, and 4 respectively.
YN372463 Glecaprevir 1365970-03-1
Glecaprevir is a hepatitis C virus (HCV) nonstructural (NS) protein 3/4A protease inhibitor that targets the the viral RNA replication. It displays IC50 values ranging from 3.5 to 11.3 nM for clinical isolates of HCV geno...
YN372283 Grazoprevir sodium salt 1425038-27-2
Grazoprevir sodium salt (MK-5172 sodium salt) is a selective inhibitor ofHepatitis C virus NS3/4aprotease with broad activity across genotypes and resistant variants, with Kis of 0.01nM (gt1b), 0.01nM (gt1a), 0.08nM (gt2a), 0.1...
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