Bombesin is a tetradecapeptide originally isolated from frog skin; plays an important role in the release of gastrin and the activation of G-protein receptors.
Kuwanon G is a flavonoid isolated fromMorus alba, acts as abombesin receptorantagonist, with potential antimicrobial activity.
Kuwanon H is a flavonoid isolated fromMorus bombycis, which acts as a potent non-peptidebombesin receptorantagonist. Kuwanon H selectively inhibits binding of gastrin releasing peptide CRP toGRP-preferring recepotr, with aKivalu...
BA 1 is a potent bombesin receptor agonist (IC50 values are 0.26, 1.55 and 2.52nM for BB1, BB2 and BB3 respectively). BA 1 enhances glucose transport in obese and diabetic primary myocytes. BA 1 also stimulates NCI-H...
PD176252 is a potent antagonist of neuromedin-B preferring (BB1) and gastrin-releasing peptide-preferring (BB2) receptor with Kis of 0.17nM and 1nM for human BB1 and BB2receptors, and 0.66nM, 16nM for Rat BB1 and ...
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