Jatrorrhizine hydroxide
Cat. No. :YN321732
CAS No. :483-43-2
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order@ubiochem.com| Product Name: | Jatrorrhizine hydroxide |
| CAS NO.: | 483-43-2 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 355.38 |
| Molecular Formula: | C₂₀H₂₁NO₅ |
| SMILES: | COC1=C(OC)C2=C[N+]3=C(C4=CC(OC)=C(O)C=C4CC3)C=C2C=C1.[OH-] |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Jatrorrhizine hydroxide is an alkaloid isolated fromCoptis chinensiswith neuroprotective, antimicrobial, antiplasmodial and antioxidant activities. Jatrorrhizine hydroxide is a potent and orally active inhibitor ofAChE(IC50=872nM) over >115-fold selectivity for BuChE. Jatrorrhizine hydroxide reduces uptake ofserotonin (5-HT) and norepinephrine (NE)via inhibition of uptake-2 transporters. |
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