Alosetron (Hydrochloride(1:X))
Cat. No. :YN321294
CAS No. :132414-02-9
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Product Name: | Alosetron (Hydrochloride(1:X)) |
CAS NO.: | 132414-02-9 |
Chemical Name: | |
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Molecular Weight: | NA |
Molecular Formula: | C₁₇H₁₈N₄O.xHCl |
SMILES: | O=C1N(CC2=C(NC=N2)C)CCC(N3C)=C1C4=C3C=CC=C4.[F,Cl,Br,I][ClH] |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Alosetron (GR 68755) Hydrochloride(1:X) is a potent and highly selective serotonin5-HT3 receptorantagonist. Alosetron Hydrochloride(1:X) is used for the research of irritable bowel syndrome (IBS). Alosetron Hydrochloride(1:X) blocks the fast 5HT3-mediated depolarisation of guinea-pig myenteric and submucosal neurons, with IC50at ~55nM. Alosetron Hydrochloride(1:X) attenuates the visceral nociceptive effect of rectal distension in conscious or anaesthetised dogs. Anti-inflammatory effects. |
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