(±)-Huperzine A
Cat. No. :YN380121
CAS No. :120786-18-7
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Product Name: | (±)-Huperzine A |
CAS NO.: | 120786-18-7 |
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Molecular Weight: | 242.32 |
Molecular Formula: | C₁₅H₁₈N₂O |
SMILES: | O=C1C=CC(C(/C2=C/C)(N)CC(C)=CC2C3)=C3N1 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | (±)-Huperzine A, an active Lycopodium alkaloid extracted from traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheimer's disease (AD). (±)-Huperzine A exhibited protective effects against d-gal-induced hepatotoxicity and inflamm-aging by inhibiting AChE activity and via the activation of the cholinergic anti-inflammatory pathway. The (±)-Huperzine A mechanism might be involved in the inhibition of DAMPs-mediated NF-κB nuclear localization and activation. (±)-Huperzine A is a potential therapeutic agent for Alzheimer's disease. |
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