Timosaponin AIII
Cat. No. :YN380235
CAS No. :41059-79-4
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Product Name: | Timosaponin AIII |
CAS NO.: | 41059-79-4 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 740.92 |
Molecular Formula: | C₃₉H₆₄O₁₃ |
SMILES: | C[C@@]12[C@]([C@@H]3C)([H])[C@](O[C@]34CC[C@H](C)CO4)([H])C[C@@]1([H])[C@@](CC[C@@]5([H])[C@@]6(CC[C@H](O[C@@](O[C@H](CO)[C@H](O)[C@@H]7O)([H])[C@@H]7O[C@]([C@@H]([C@@H](O)[C@@H]8O)O)([H])O[C@@H]8CO)C5)C)([H])[C@]6([H])CC2 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Timosaponin A3 triggers liver injury through inducing ROS generation and suppressing the expression of BA transporters. Timosaponin A3 has selectively cytotoxic for cancer versus normal cells, the selective cytotoxic properties of it could be related to the inhibition of major oncogenic pathways and induction of ER stress. Timosaponin A3 and Sarsasapogenin can inhibit nuclear factor-kB and p38 signaling in TNF-a stimulated BV2 microglia cells, they have the therapeutic potential for various neurodegenerative diseases caused by inflammation. Timosaponin A3 has application for reducing blood sugar and treating type-B diabete. |
IC50&Target: | |
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In Vivo: | |
Clinical Trial: | |
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References: |
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