LCZ696
Cat. No. :YN321181
CAS No. :936623-90-4
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5mg
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Product Name: | LCZ696 |
CAS NO.: | 936623-90-4 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 957.99 |
Molecular Formula: | C₄₈H₆₀N₆Na₃O₁₀.₅ |
SMILES: | O=C(CCC(O[Na])=O)N([C@H](CC(C=C1)=CC=C1C2=CC=CC=C2)C[C@@H](C)C(OCC)=O)[H].O=C(O[Na])[C@@H](N(C(CCCC)=O)CC3=CC=C(C4=CC=CC=C4C5=NN=NN5[Na])C=C3)C(C)C.[2.5H2O] |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | LCZ696 (Sacubitril/Valsartan), comprised Valsartan (an ARB) and Sacubitril (AHU377) in 1:1 molar ratio, is a first-in-class, orally bioavailable, and dual-actingangiotensin receptor-neprilysin (ARN)inhibitor for hypertension and heart failure . LCZ696 ameliorates diabetic cardiomyopathy by inhibiting inflammation, oxidative stress and apoptosis. |
IC50&Target: | |
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Clinical Trial: | |
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References: |
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