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Olodanrigan

Cat. No. :YN320688

  • CAS No. :1316755-16-4

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    • Products Infomation
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    • Product Name:Olodanrigan
      CAS NO.:1316755-16-4
      Chemical Name:
      Synonyms:PD-126055, (S) PD-126055
      Molecular Weight:507.58
      Molecular Formula:C₃₂H₂₉NO₅
      SMILES:O=C([C@H]1N(C(C(C2=CC=CC=C2)C3=CC=CC=C3)=O)CC4=C(C(OCC5=CC=CC=C5)=C(OC)C=C4)C1)O
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:Olodanrigan (EMA401, PD-126055, (S) PD-126055) is a highly selective, orally active, peripherally restricted antagonist of angiotensin II type 2 receptor (AT2R). Olodanrigan (EMA401) analgesic action appears to involve the inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons.
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