Losartan Carboxylic Acid
Cat. No. :YN320641
CAS No. :124750-92-1
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order@ubiochem.com| Product Name: | Losartan Carboxylic Acid |
| CAS NO.: | 124750-92-1 |
| Chemical Name: | |
| Synonyms: | E-3174 |
| Molecular Weight: | 436.89 |
| Molecular Formula: | C₂₂H₂₁ClN₆O₂ |
| SMILES: | O=C(C1=C(Cl)N=C(CCCC)N1CC2=CC=C(C3=CC=CC=C3C4=NNN=N4)C=C2)O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Losartan Carboxylic Acid (E-3174, EXP-3174), an active carboxylic acid metabolite of Losartan, is a non-peptide angiotensin II (AT1) receptor antagonist. Losartan Carboxylic Acid inhibits the specific binding of [125I]-angiotensin II to VSMC with IC50 of 1.1 nM. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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