Tunicamycin
Cat. No. :YN250867
CAS No. :11089-65-9
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Product Name: | Tunicamycin |
CAS NO.: | 11089-65-9 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 844.94 (n=10) |
Molecular Formula: | C₃₉H₆₄N₄O₁₆ |
SMILES: | O=C1NC(N([C@H]2[C@H](O)[C@H](O)[C@@H](C(C[C@@H]3[C@H](O)[C@H](O)[C@@H](NC(/C=C/[(CH2) 8-11]C(C)C)=O)[C@H](O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4NC(C)=O)O3)O)O2)C=C1)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibitsN-linked glycosylation and blocksGlcNAc phosphotransferase (GPT). Tunicamycin causes accumulation of unfolded proteins in cell endoplasmic reticulum (ER) and induces ER stress, and causes blocking of DNA synthesis and cell cycle arrest in G1 phase. Tunicamycin inhibitsgram-positive bacteria,yeasts,fungi, and viruses and has anti-cancer activity .Tunicamycin increases exosome release in cervical cancer cells. |
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References: |
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