AMG 487
Cat. No. :YN320962
CAS No. :473719-41-4
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order@ubiochem.com| Product Name: | AMG 487 |
| CAS NO.: | 473719-41-4 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 603.59 |
| Molecular Formula: | C₃₂H₂₈F₃N₅O₄ |
| SMILES: | O=C(N([C@@H](C1=NC2=NC=CC=C2C(N1C3=CC=C(OCC)C=C3)=O)C)CC4=CC=CN=C4)CC5=CC=C(OC(F)(F)F)C=C5 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | AMG 487 is an orally active and selective CXC chemokine receptor 3 (CXCR3) antagonist that inhibits the binding of IP-10 (CXCL10) and ITAC (CXCL11) to CXCR3 with IC50 of 8.0 nM and 8.2 nM, respectively. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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