Motixafortide
Cat. No. :YN321794
CAS No. :664334-36-5
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order@ubiochem.com| Product Name: | Motixafortide |
| CAS NO.: | 664334-36-5 |
| Chemical Name: | |
| Synonyms: | BKT140, TF 14016, 4-fluorobenzoyl, 4F-benzoyl-TN14003, T140 |
| Molecular Weight: | 2159.52 |
| Molecular Formula: | C₉₇H₁₄₄FN₃₃O₁₉S₂ |
| SMILES: | [4F-Benzoyl-RR-{2-Naph-Ala}-CY-{Cit}-KKPYR-{Cit}-CR-NH2 (Disulfide bridge: Cys4-Cys13)] |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Motixafortide (BL-8040, BKT140, TF 14016, 4-fluorobenzoyl, 4F-benzoyl-TN14003, T140) is an antagonist of CXCR4 with IC50 of ～1 nM. BL-8040 induces the apoptosis of AML blasts by down-regulating ERK, BCL-2, MCL-1 and cyclin-D1 via altered miR-15a/16-1 expression. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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