YN320524 BAY 38-7271 212188-60-8

BAY 38-7271 is selective and highly potent and cannabinoidCB1/CB2receptoragonist, with Kis of 1.85nM and 5.96nM for recombinant human CB1receptor and CB2receptor, respectively. BAY 38-7271 has strong neuroprotective...

YN320914 (±)-Ibipinabant 362519-49-1

(±)-Ibipinabant ((±)-SLV319) is the racemate of SLV319. (±)-Ibipinabant ((±)-SLV319) is a potent and selective cannabinoid-1 (CB-1) receptor antagonist with an IC50 of 22nM.

YN320049 Bay 59-3074 406205-74-1

Bay 59-3074 is a selective cannabinoidCB1/CB2receptorpartial agonist with Ki values of 48.3 and 45.5nM at human CB1 and CB2 receptors, respectively. Bay 59-3074 has analgesic properties.

YN321846 Hemopressin(rat) 568588-77-2

Hemopressin(rat) is a nonapeptide derived from the α1-chain of hemoglobin, is originally isolated from rat brain homogenates. Hemopressin(rat) is orally active, selective and inverse agonist ofCB1cannabinoid receptors. Hemopressin(r...

YN320503 CB1 antagonist 2 614726-85-1

CB1 antagonist 2 is caimabinoid 1 (CB1) antagonist extracted from patent WO2016184310A1, compound 3, inhibits CB1 in vivo with an IC50 of 25.5nM.

YN320828 GW842166X 666260-75-9

GW842166X is a potent and highly selective agonist of cannabinoid receptor CB2 receptor with EC50 of 63 nM, shows no significant activity at CB1 receptor. Phase 2.

YN320382 Otenabant 686344-29-6

Otenabant is a potent and selectivecannabinoid receptor CB1antagonist with Kiof 0.7nM, exhibits 10,000-fold greater selectivity against human CB2 receptor.

YN320006 Taranabant racemate 701977-00-6

Taranabant racemate (MK-0364 racemate) is an antagonist and /or inverse agonist of the Cannabinoid-1(CB1) receptorextracted from patent WO 2004048317 A1.

YN320007 Taranabant ((1R,2R)stereois... 701977-08-4

Taranabant (1R,2R)stereoisomer is the R-enantiomer of Taranabant. Taranabant is a highly potent and selectivecannabinoid 1(CB1) receptor inverse agonist.

YN320005 Taranabant 701977-09-5

Taranabant is a highly potent and selectivecannabinoid 1(CB1) receptor inverse agonist that inhibits the binding and functional activity of various agonists, with a bindingKiof 0.13nM for the human CB1R in vitro.

YN320715 Org 27569 868273-06-7

Org 27569 is a potentCB1 receptorallosteric modulator, which increases agonist binding, yet blocks agonist-induced CB1 signaling.

YN320214 Ridaifen-B 886465-70-9

Ridaifen-B (RID-B) is a potent antagonist ofestrogen receptor α (ERα)with IC50 of 52.4nM, a tamoxifen (HY-13757A) derivative. Ridaifen-B is a high affinity, selective, inverse agonist atCB2receptor (Ki=43.7nM) over 17...

YN322084 CB1 antagonist 1 890037-68-0

CB1 antagonist 1 is an antagonist ofCB1 receptor, used in the research of metabolic syndrome and obesity, neuroinflammatory disorders, cognitive disorders and psychosis, gastrointestinal disorders, and cardiovascular conditions.

YN320639 A-836339 959746-77-1

A-836339 is a cannabinoid CB2 receptor-selective agonist; exhibits high potencies at CB(2) and selectivity over CB(1) receptors.in vitro: In radiolig and binding assays, A-836339 displays high affinities at CB(2) receptors an...

YN320992 MDA 19 1048973-47-2

MDA 19 is a potent and selective agonist of humancannabinoid receptor 2 (CB2), with a Ki of 43.3nM. MDA 19 has antiallodynic effects in a rat model of neuropathic pain and does not affect rat locomotor activity.

YN321071 LY2828360 1231220-79-3

LY2828360 is a slowly acting but efficacious G protein-biased cannabinoid(CB2)agonist, inhibiting cAMP accumulation and activating ERK1/2 signaling.

YN320454 TM38837 1253641-65-4

TM38837 is a peripheral selectivecannabinoid receptor type 1 (CB1)receptor antagonist. TM38837 shows limited penetrance to the brain in order to minimize or prevent CNS adverse reactions, and preserves potential antiobesity effec...

YN320428 Olorinab 1268881-20-4

Olorinab (APD 371) is a highly potent, selective and fully efficacious cannabinoid receptor type 2(CB2)agonist, with an EC50 of 6.2nM for hCB2.

YN321847 Hemopressin (human, mouse) 1314035-51-2

Hemopressin is a nonapeptide derived from the α1-chain of hemoglobin, is originally isolated from rat brain homogenates. Hemopressin is orally active, selective and inverse agonist ofCB1cannabinoid receptors. Hemopressin exerts anti...

YN321194 JD-5037 1392116-14-1

JD-5037 is a peripherally restricted (PR) cannabinoid-1 receptor blocker with an IC50 value of 2 nM for CB1 receptor and > 1000 nM for CB2 receptor.