Olodanrigan
Cat. No. :YN320688
CAS No. :1316755-16-4
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5mg
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Product Name: | Olodanrigan |
CAS NO.: | 1316755-16-4 |
Chemical Name: | |
Synonyms: | PD-126055, (S) PD-126055 |
Molecular Weight: | 507.58 |
Molecular Formula: | C₃₂H₂₉NO₅ |
SMILES: | O=C([C@H]1N(C(C(C2=CC=CC=C2)C3=CC=CC=C3)=O)CC4=C(C(OCC5=CC=CC=C5)=C(OC)C=C4)C1)O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Olodanrigan (EMA401, PD-126055, (S) PD-126055) is a highly selective, orally active, peripherally restricted antagonist of angiotensin II type 2 receptor (AT2R). Olodanrigan (EMA401) analgesic action appears to involve the inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons. |
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