JNJ-10229570
Cat. No. :YN320315
CAS No. :524923-88-4
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order@ubiochem.com| Product Name: | JNJ-10229570 |
| CAS NO.: | 524923-88-4 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 389.47 |
| Molecular Formula: | C₂₂H₁₉N₃O₂S |
| SMILES: | COC1=C(C=CC=C1)C(N(C2=C(C=CC=C2)OC)S/3)=NC3=NC4=CC=CC=C4 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | JNJ-10229570 is an antagonist ofmelanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gl and differentiation and the production of sebum-specific lipids. JNJ-10229570 inhibits the binding of125I-NDP-α-MSH to cells expressing human MC1R and MC5R, with IC50 values of 270nM and 200nM, respectively. |
| IC50&Target: | |
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