CCR6 inhibitor 1
Cat. No. :YN320458
CAS No. :2437547-04-9
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order@ubiochem.com| Product Name: | CCR6 inhibitor 1 |
| CAS NO.: | 2437547-04-9 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 504.52 |
| Molecular Formula: | C₂₄H₂₃F₃N₄O₃S |
| SMILES: | O=S([C@H](CC1)CC[C@@H]1NC2=NC=C(C(F)(F)F)C=C2)(C3=CC=C(C4=CC=NC(C(N)=O)=C4)C=C3)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | CCR6 inhibitor 1 is a potent and selectiveCCR6inhibitor, with IC50s of 0.45 and 6nM for monkey and human CCR6, much more selective at CCR6 over human CCR1 (IC50, > 30000nM), and CCR7 (IC50, 9400nM). CCR6 inhibitor 1 markedly blocks ERK phosphorylation. CCR6 inhibitor 1 is used in the research of autoimmune diseases and cancer. |
| IC50&Target: | |
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