Kaempferitrin
Cat. No. :YN440424
CAS No. :482-38-2
86-020-82000279
sales@ubiochem.com
order@ubiochem.com| Product Name: | Kaempferitrin |
| CAS NO.: | 482-38-2 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 578.52 |
| Molecular Formula: | C₂₇H₃₀O₁₄ |
| SMILES: | O=C1C(O[C@H](O[C@@H](C)[C@H](O)[C@H]2O)[C@@H]2O)=C(C3=CC=C(O)C=C3)OC4=CC(O[C@H](O[C@@H](C)[C@H](O)[C@H]5O)[C@@H]5O)=CC(O)=C14 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Kaempferitrin has an acute lowering effect on blood glucose in diabetic rats and to stimulate the glucose uptake percentile, as efficiently as insulin in muscle from normal rats. Kaempferitrin improves insulin resistance by the activation of the classical insulin transduction pathway, and increases adiponectin secretion. Kaempferitrin exerts cytotoxic and antitumor effects against HeLa cells, the general mechanisms include cell cycle arrest in G1 phase and apoptosis via intrinsic pathway in a caspase dependent pathway. Kaempferitrin exerts immunostimulatory effects on immune responses mediated by splenocytes, macrophages, peripheral blood mononuclear cells (PBMC) and NK cells. Kaempfertrin possesses significant antiosteoporotic activity, it can significantly improve the bone mass and microarchitecture in ovariectomized (OVX) rats. Kaempferitrin has antidepressant-like effect, the effect is related to the serotonergic system, principally 5-HT1A. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
TELL : +86-020-82000279
Add:Room 519, Block F, Guangzhou International Business Incubator, No.3 Lanyue Road, Science Town, Huangpu District, Guangzhou, China.
