SB-674042
Cat. No. :YN320391
CAS No. :483313-22-0
86-020-82000279
sales@ubiochem.com
order@ubiochem.com| Product Name: | SB-674042 |
| CAS NO.: | 483313-22-0 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 448.51 |
| Molecular Formula: | C₂₄H₂₁FN₄O₂S |
| SMILES: | FC1=C(C2=C(C(N3[C@H](CC4=NN=C(C5=CC=CC=C5)O4)CCC3)=O)N=C(C)S2)C=CC=C1 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | SB-674042 is a potent and selective non-peptide orexin OX1 receptor antagonist (Kd = 3.76nM); exhibits 100-fold selectivity for OX1 over OX2 receptors. SB-674042 has no effect at serotonergic, dopaminergic, adrenergic or purinergic receptors. Inhibits orexin 1-induced Ca2+ mobilization in CHO-DG44 cells stably transfected with the OX1 receptor. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
TELL : +86-020-82000279
Add:Room 519, Block F, Guangzhou International Business Incubator, No.3 Lanyue Road, Science Town, Huangpu District, Guangzhou, China.
