Galantide
Cat. No. :YN321827
CAS No. :138579-66-5
Product Name: | Galantide |
CAS NO.: | 138579-66-5 |
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Molecular Weight: | 2199.53 |
Molecular Formula: | C₁₀₄H₁₅₁N₂₅O₂₆S |
SMILES: | [GWTLNSAGYLLGPQQFFGLM-NH2] |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Galantide, a non-specificgalanin receptorantagonist, is a peptide consisting of fragments of galanin and substance P. Galantide recognizes two classes of galanin binding sites (KD<0.1nM and ~6nM) in the rat hypothalamus. Galantide dose dependently (IC50=1.0nM) antagonizes the galanin-mediated inhibition of the glucose-induced insulin secretion from mouse pancreatic islets. Galantide appears to bind to a single population of SP receptors (KD~40nM) . |
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