JNJ-39758979
Cat. No. :YN320107
CAS No. :1046447-90-8
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order@ubiochem.com| Product Name: | JNJ-39758979 |
| CAS NO.: | 1046447-90-8 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 221.30 |
| Molecular Formula: | C₁₁H₁₉N₅ |
| SMILES: | NC1=NC(C(C)C)=CC(N2C[C@H](N)CC2)=N1 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | JNJ-39758979 is a selective, orally active, and high-affinityhistamine H4receptorantagonist with Kis of 12.5, 5.3, and 25nM for human, mouse, and monkey histamine H4receptor, respectively. JNJ-39758979 functionally antagonizes histamine-induced cAMP inhibition with a pA2 of 7.9 in transfected cells. JNJ-39758979 shows good anti-inflammatory and antipruritic activity. |
| IC50&Target: | |
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