Timapiprant sodium
Cat. No. :YN320966
CAS No. :950688-14-9
86-020-82000279
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order@ubiochem.com| Product Name: | Timapiprant sodium |
| CAS NO.: | 950688-14-9 |
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| Molecular Weight: | 370.35 |
| Molecular Formula: | C₂₁H₁₆FN₂NaO₂ |
| SMILES: | O=C(O[Na])CN1C2=CC=C(F)C=C2C(CC3=NC4=C(C=CC=C4)C=C3)=C1C |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Timapiprant sodium (OC000459 sodium) is a potent, selective, and orally active D prostanoid receptor 2 (DP2, also known asCRTH2) antagonist. Timapiprant sodium (OC000459 sodium) potently displaces [3H] PGD2 from human recombinant DP2(Ki=13nM), rat recombinant DP2(Ki=3nM), and human native DP2(Ki=4nM). Timapiprant sodium (OC000459 sodium) inhibits mast cell activation of Th2 lymphocytes and eosinophils. |
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