A-192621
Cat. No. :YN320532
CAS No. :195529-54-5
Pack size
price
inventory
5mg
Enquiry
Enquiry
10mg
Enquiry
Enquiry
25mg
Enquiry
Enquiry
50mg
Enquiry
Enquiry
86-020-82000279
sales@ubiochem.com
order@ubiochem.com| Product Name: | A-192621 |
| CAS NO.: | 195529-54-5 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 558.66 |
| Molecular Formula: | C₃₃H₃₈N₂O₆ |
| SMILES: | O=C([C@H]1[C@H](C2=CC=C(OCCC)C=C2)N(CC(NC3=C(CC)C=CC=C3CC)=O)C[C@@H]1C4=CC=C(OCO5)C5=C4)O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | A-192621 is a potent, nonpeptide, orally active and selectiveendothelin B (ETB) receptorantagonist with an IC50 of 4.5nM and a Ki of 8.8nM. The selectivity of A-192621 is 636-fold higher than ETA(IC50 of 4280nM and Kiof 5600nM). A-192621 promotesapoptosisin PASMCs. A-192621 alos causes elevation of arterial blood pressure and an elevation in the plasma ET-1 level . |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
TELL : +86-020-82000279
Add:Room 519, Block F, Guangzhou International Business Incubator, No.3 Lanyue Road, Science Town, Huangpu District, Guangzhou, China.
