Cyclic ADP-ribose
Cat. No. :YN361015
CAS No. :119340-53-3
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Product Name: | Cyclic ADP-ribose |
CAS NO.: | 119340-53-3 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 541.30 |
Molecular Formula: | C₁₅H₂₁N₅O₁₃P₂ |
SMILES: | O[C@H]([C@@H]1O)[C@](O[C@]1([H])COP(O)(OP(O)(OC2)=O)=O)([H])N3C(N=CN([C@]4([H])O[C@@]2([H])[C@@H](O)[C@H]4O)C5=N)=C5N=C3 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Cyclic ADP-ribose (cADPR) is a potent second messenger forcalcium mobilizationthat is synthesized from NAD+by a ADP-ribosyl cyclase. Cyclic ADP-ribose increases cytosolic calcium mainly byRyanodine receptor-mediated release from endoplasmic reticulum and also by extracellular influx through the opening ofTRPM2 channels. |
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