Relacorilant
Cat. No. :YN320398
CAS No. :1496510-51-0
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5mg
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Product Name: | Relacorilant |
CAS NO.: | 1496510-51-0 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 586.56 |
Molecular Formula: | C₂₇H₂₂F₄N₆O₃S |
SMILES: | O=C(C1=CC(C(F)(F)F)=CC=N1)[C@@]2(CN(S(=O)(C3=CN(C)N=C3)=O)CC4)C4=CC5=C(C=NN5C6=CC=C(F)C=C6)C2 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Relacorilant is a potent, selective and orally bioavailableglucocorticoid receptorantagonist, with a Ki of 7.2nM in HepG2 TAT assay, and also showsKis of 12, 81.2, 210nM for rat, human and monkey glucocorticoid receptor in cell-based assay, respectively. Relacorilant has the potential for Cushing’s syndrome treatment. |
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References: |
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