Coenzyme A
Cat. No. :YN371175
CAS No. :85-61-0
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order@ubiochem.com| Product Name: | Coenzyme A |
| CAS NO.: | 85-61-0 |
| Chemical Name: | |
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| Molecular Weight: | 767.53 |
| Molecular Formula: | C₂₁H₃₆N₇O₁₆P₃S |
| SMILES: | O[C@H]1[C@@H](O[C@H](COP(OP(OCC(C)([C@@H](O)C(NCCC(NCCS)=O)=O)C)(O)=O)(O)=O)[C@H]1OP(O)(O)=O)N2C3=NC=NC(N)=C3N=C2 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Coenzyme A is is an obligatory cofactor in all living cells synthesised from pantothenate (Vitamin B5), adenosine triphosphate (ATP) and cysteine. Covalent binding of Coenzyme A to Peroxiredoxin 5 (Prdx5) results in complete inhibition of its peroxidase activity, which is reversed by reduction with DTT.Coenzyme A and its thioester derivatives are key players in major catabolic and anabolic pathways and the regulation of gene expression. Many human pathologies, including cancer, diabetes and neurodegeneration, have been associated with abnormal biosynthesis and homeostasis of CoA and its derivatives. |
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