4-Methyl-2-oxopentanoic acid
Cat. No. :YN374181
CAS No. :816-66-0
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order@ubiochem.com| Product Name: | 4-Methyl-2-oxopentanoic acid |
| CAS NO.: | 816-66-0 |
| Chemical Name: | |
| Synonyms: | Ketoleucine, 4-MOV, KIC, 4-Methyl-2-oxopentanoic acid, alpha-Ketoisocaproic acid, alpha-ketoisocaproate, 2-Oxoisohexanoate |
| Molecular Weight: | 130.14 |
| Molecular Formula: | C₆H₁₀O₃ |
| SMILES: | CC(C)CC(C(O)=O)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | 4-Methyl-2-oxovaleric acid (Ketoleucine, 4-MOV, KIC, 4-Methyl-2-oxopentanoic acid, alpha-Ketoisocaproic acid, alpha-ketoisocaproate, 2-Oxoisohexanoate) is released by Astrocytes to neurons and can be reaminated by aminotransferase to leucine. 4-Methyl-2-oxovaleric acid reduces the rate of protein degradation in skeletal muscle. 4-Methyl-2-oxovaleric acid acts as an uncoupler of oxidative phosphorylation (OXPHOS) and as a metabolic inhibitor possibly through its inhibitory effect on alpha-ketoglutarate dehydrogenase (oxoglutarate dehydrogenase complex, OGDC) activity. |
| IC50&Target: | |
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| References: |
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