L-2-Hydroxyglutaric acid
Cat. No. :YN370618
CAS No. :13095-48-2
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Product Name: | L-2-Hydroxyglutaric acid |
CAS NO.: | 13095-48-2 |
Chemical Name: | |
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Molecular Weight: | 148.11 |
Molecular Formula: | C₅H₈O₅ |
SMILES: | O=C(O)[C@@H](O)CCC(O)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | L-2-Hydroxyglutaric acid is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid can inhibithistone demethylases and hence promote histone methylation. L-2-Hydroxyglutaric acid inhibitsmitochondrial creatine kinase(Mi-CK) activity with Km and Kiof 2.52 mM and 11.13 mM, respectively. |
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