SAICAR
Cat. No. :YN371071
CAS No. :3031-95-6
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order@ubiochem.com| Product Name: | SAICAR |
| CAS NO.: | 3031-95-6 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 454.28 |
| Molecular Formula: | C₁₃H₁₉N₄O₁₂P |
| SMILES: | O=C(O)C[C@@H](C(O)=O)NC(C1=C(N)N([C@H]2[C@@H]([C@@H]([C@@H](COP(O)(O)=O)O2)O)O)C=N1)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | SAICAR is an intermediate ofde novopurine nucleotide biosynthesis, activatespyruvate kinase isoform M2 (PKM2)in an isozyme-selective manner, with an EC50 of 0.3 mM. SAICAR stimulates PKM2 and promotes cancer cell survival in glucose-limited conditions. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
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