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Endogenous Metabolite

Chemical structure

Cat.No.

Product Name

CAS no.

Target

  • YN374169 H-D-Trp-OH 153-94-6

    H-D-Trp-OH is a D-stereoisomer of tryptophan and occasionally found in naturally produced peptides such as the marine venom peptide.

  • YN374353 5-Hydroxytryptophol 154-02-9

    5-Hydroxytryptophol is a mammalian serotonin metabolite, acting as a marker of acute alcohol consumption.

  • YN371786 6-Thioguanine 154-42-7

    Thioguanine, a purine antimetabolite, inhibits DNMT1 activity through ubiquitin-targeted degradation, used in the treatment of acute lymphoblastic leukemia, autoimmune disorders (e.g., Crohn's disease, rheumatoid arthritis) and organ ...

  • YN370630 1,5-Anhydrosorbitol 154-58-5

    1,5-Anhydrosorbitol is a short-term marker for glycemic control.

  • YN370631 Thiamine pyrophosphate 154-87-0

    Thiamine pyrophosphate hydrochloride is a thiamine (vitamin B1) derivative which is produced by the enzyme thiamine diphosphokinase. It is a coenzyme of many enzymes, most of which occur in prokaryotes and is involved in the regulation o...

  • YN374218 Ac-Arg-OH 155-84-0

    Ac-Arg-OH is one of the guanidino compounds found elevated in the serum of an hemodialyzed renal insufficient (uremic) pediatric population.

  • YN374172 Phenylpyruvic acid 156-06-9

    Phenylpyruvic acid is used in the synthesis of 3-phenyllactic acid (PLA) by lactate dehydrogenase.

  • YN373227 4-Hydroxyphenylacetic acid 156-38-7

    4-hydroxyphenylacetic acid, a major microbiota-derived metabolite of polyphenols, is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression ofNrf2.

  • YN374103 4-​Hydroxyphenylpyruvic acid 156-39-8

    4-Hydroxyphenylpyruvic acid is an intermediate in the metabolism of the amino acid phenylalanine.

  • YN374074 H-HoArg-OH 156-86-5

    H-HoArg-OH (L-Homoarginine) is an organ-specific, uncompetitive inhibitor of human liver and bone alkaline phosphohydrolases.

  • YN370632 Argininic acid 157-07-3

    Argininic acid is an α-amino acid that is used in the biosynthesis of proteins.

  • YN374078 Norharmane 244-63-3

    Norharmane (Norharman), isolated from coffee, is a potent and selectivemonoamine oxidase A(MAO-A) inhibitor with a Ki of 3.34μM.

  • YN372674 1H-pyrazole 288-13-1

    Pyrazole (1H-pyrazole) is a five membered heteroaromatic ring with two nitrogen atoms is of immense significance. Pyrazole is an indispensable anchor for design and development of new pharmacological agents.

  • YN374407 Pyrimidine 289-95-2

    Pyrimidine is an endogenous metabolite.

  • YN372694 Glyoxalic acid 298-12-4

    Glyoxalic acid (NSC 27785) is an organic compound that is both an aldehyde and a carboxylic acid.

  • YN370770 3-O-Methyldopa 300-48-1

    3-O-Methyldopa (3-Methoxy-L-tyrosine) is a metabolite of L-DOPA which is formed by catechol-O-methyltransferase (COMT). 3-O-Methyldopa competitively inhibits the pharmacodynamics of l-DOPA and dopamine.

  • YN370103 Hypotaurine 300-84-5

    Hypotaurine (2-aminoethanesulfinic acid), an intermediate in taurine biosynthesis from cysteine in astrocytes, is an endogenous inhibitory amino acid of theglycine receptor.

  • YN370743 3-Hydroxybutyric acid 300-85-6

    3-Hydroxybutyric acid (β-Hydroxybutyric acid) is a metabolite that is elevated in type I diabetes. 3-Hydroxybutyric acid can modulate the properties of membrane lipids.

  • YN373272 Oleamide 301-02-0

    Oleamide is an endogenous fatty acid amide which can be synthesized de novo in the mammalian nervous system, and has been detected in human plasma.

  • YN372214 Retinoic acid 302-79-4

    Tretinoin, which is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), can induce granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells.

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