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Fosmanogepix

Cat. No. :YN250283

  • CAS No. :2091769-17-2

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    • Product Name:Fosmanogepix
      CAS NO.:2091769-17-2
      Chemical Name:
      Synonyms:
      Molecular Weight:468.40
      Molecular Formula:C₂₂H₂₁N₄O₆P
      SMILES:O=P(OC[N]1=CC=CC(C2=CC(CC3=CC=C(COC4=NC=CC=C4)C=C3)=NO2)=C1N)(O)[O].[+].[-]
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:Fosmanogepix (APX001) is a first-in-class  and  orally available broad-spectrumantifungalagent, which targets the highly conservedGwt1fungal enzyme. Fosmanogepix (APX001) is an N-phosphonooxymethyl prodrug which is rapidly  and  completely metabolized by systemic alkaline phosphatases to the active moiety, APX001A. Fosmanogepix (APX001) can be used in development for the treatment of invasive fungal infections.
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